Bench‐Stable Manganese NHC Complexes for the Selective Reduction of Esters to Alcohols with Silanes
Sara C. A. Sousa, Sara Realista, Beatriz Royo
Abstract
Abstract Selective reduction of esters to alcohols was accomplished through Mn(I)‐mediated hydrosilylation reaction. The manganese tricarbonyl complex [Mn(bis‐NHC)(CO) 3 Br] resulted an active pre‐catalyst for the reduction of a variety of esters using phenylsilane and the cheap and readily available polymethylhydrosiloxane. An in situ examination of the catalytic reaction using 55 Mn NMR spectroscopy allowed us to detect the formation of Mn(I) intermediate active species. magnified image
Topics & Concepts
PhenylsilaneHydrosilylationChemistryManganeseSilanesCatalysisOrganic chemistryIn situSelective reductionMedicinal chemistrySilaneOrganoboron and organosilicon chemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryAsymmetric Hydrogenation and Catalysis