Elevated SIRT3 Parkin-dependently activates cell mitophagy to ameliorate TNF-α-induced psoriasis-related phenotypes in HaCaT cells through deacetylating FOXO3a for its activation
Yanli Ma, Yu Wang, LI Yu-zhen
Topics & Concepts
HaCaTMitophagyParkinSIRT3PsoriasisTumor necrosis factor alphaSirtuinCell biologyInflammationCancer researchBiologyChemistryAutophagyIn vitroImmunologyMedicineApoptosisBiochemistryInternal medicineAcetylationDiseaseGeneParkinson's diseaseAutophagy in Disease and TherapySirtuins and Resveratrol in MedicineCalcium signaling and nucleotide metabolism