Crystallographic study, biological evaluation and DFT/POM/Docking analyses of pyrazole linked amide conjugates: Identification of antimicrobial and antitumor pharmacophore sites
Mohammed Chalkha, Abdelfattah El Moussaoui, Taïbi Ben Hadda, Malika Berredjem, Abdeslem Bouzina, Faisal A. Almalki, Hamza Saghrouchni, Mohamed Bakhouch, Mohamed Saadi, Lahcen El Ammari, Magda H. Abdellatiif, Mohamed El Yazidi
Topics & Concepts
ChemistryPharmacophoreAntimicrobialDocking (animal)Hydrogen bondCombinatorial chemistryPyrazoleStereochemistryMoleculeAmideLipinski's rule of fiveOrganic chemistryIn silicoBiochemistryNursingGeneMedicineSynthesis and biological activityChemical synthesis and pharmacological studiesSynthesis and Characterization of Heterocyclic Compounds