AMX – the highly automated macromolecular crystallography (17-ID-1) beamline at the NSLS-II
Dieter K. Schneider, Alexei S. Soares, Edwin Lazo, Dale F. Kreitler, Kun Qian, Martin R. Fuchs, Dileep Bhogadi, Steve Antonelli, Stuart S. Myers, Bruno Martins, John M. Skinner, Jun Aishima, H. J. Bernstein, Thomas Langdon, John Lara, Robert Petkus, Matt Cowan, Leonid Flaks, Thomas J. Smith, Grace Shea-McCarthy, Mourad Idir, Lei Huang, Oleg Chubar, Robert M. Sweet, L. E. Berman, Seán McSweeney, Jean Jakoncic
Abstract
), micro-focus (7 µm × 5 µm), low-divergence (1 mrad × 0.35 mrad) energy-tunable (5-18 keV) beamline at the NSLS-II, Brookhaven National Laboratory, Upton, NY, USA. It is one of the three life science beamlines constructed by the NIH under the ABBIX project and it shares sector 17-ID with the FMX beamline, the frontier micro-focus macromolecular crystallography beamline. AMX saw first light in March 2016 and started general user operation in February 2017. At AMX, emphasis has been placed on high throughput, high capacity, and automation to enable data collection from the most challenging projects using an intense micro-focus beam. Here, the current state and capabilities of the beamline are reported, and the different macromolecular crystallography experiments that are routinely performed at AMX/17-ID-1 as well as some plans for the near future are presented.