Prevention of Venous Thromboembolism in 2020 and Beyond
Matthew C. Nicholson, Noel Chan, Vinai Bhagirath, Jeffrey S. Ginsberg
Abstract
Venous thromboembolism (VTE) is the third most common cause of vascular mortality worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism (PE). In this review, we discuss how an understanding of VTE epidemiology and the results of thromboprophylaxis trials have shaped the current approach to VTE prevention. We will discuss modern thromboprophylaxis as it pertains to genetic risk factors, exogenous hormonal therapies, pregnancy, surgery, medical hospitalization, cancer, and what is known thus far about VTE in COVID-19 infection.
Topics & Concepts
MedicinePulmonary embolismVenous thromboembolismIntensive care medicineDeep veinThrombosisEpidemiologyVenous thrombosisPregnancyInternal medicineBiologyGeneticsVenous Thromboembolism Diagnosis and ManagementBlood Coagulation and Thrombosis MechanismsAcute Myocardial Infarction Research