Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines
Soraya Scuderi, Tae-Yun Kang, Alexandre Jourdon, Alex Nelson, Liang Yang, Feinan Wu, George M. Anderson, Jessica Mariani, Livia Tomasini, Vivekananda Sarangi, Alexej Abyzov, Andre Levchenko, Flora M. Vaccarino
Topics & Concepts
BiologyOrganoidWnt signaling pathwayCell biologyHuman brainCellHuman cellComputational biologyCell cultureEvolutionary biologyNeuroscienceGeneticsSignal transductionCongenital heart defects researchRNA Research and SplicingDevelopmental Biology and Gene Regulation