Continuous one-flow multi-step synthesis of active pharmaceutical ingredients
Victor R. L. J. Bloemendal, Mathilde A. C. H. Janssen, Jan C. M. van Hest, Floris P. J. T. Rutjes
Abstract
This review highlights a selection of multistep continuous flow (one-flow) processes leading to the synthesis of active pharmaceutical ingredients (APIs).
Topics & Concepts
Active ingredientContinuous flowComputer scienceFlow (mathematics)Selection (genetic algorithm)Biochemical engineeringMedicineArtificial intelligencePharmacologyMathematicsEngineeringGeometryInnovative Microfluidic and Catalytic Techniques InnovationChemical Synthesis and AnalysisAnalytical Chemistry and Chromatography