Litcius/Paper detail

When It Comes to Benchmarks, Humans Are the Only Way

Adam Rodman, Laura Zwaan, Andrew Olson, Arjun K. Manrai

2025NEJM AI16 citationsDOIOpen Access PDF

Abstract

Improved performance of large language models (LLMs) on traditional reasoning assessments has led to benchmark saturation. This has spurred efforts to develop new benchmarks, including synthetic computational simulations of clinical practice involving multiple AI agents. We argue that it is crucial to ground such efforts in extensive human validation. We conclude by providing four recommendations for researchers to better evaluate LLMs for clinical practice.

Topics & Concepts

Computer scienceComputer securityBusinessClinical Reasoning and Diagnostic SkillsComplex Systems and Decision Making