Discovery of Leishmania donovani topoisomerase IB selective inhibitors by targeting protein-protein interactions between the large and small subunits
Hyeryon Lee, Kyunghwa Baek, Trong-Nhat Phan, I Seul Park, Sang‐Chul Lee, Jiho Kim, Joo Hwan No
Topics & Concepts
Protein subunitAmastigoteLeishmania donovaniBiochemistryEnzymeLeishmaniaChemistryTopoisomeraseBiologyMolecular biologyLeishmaniasisVisceral leishmaniasisComputer scienceParasite hostingImmunologyWorld Wide WebGeneResearch on Leishmaniasis StudiesCancer therapeutics and mechanismsSynthesis and Biological Evaluation