Bisphenol analogues inhibit human and rat 17β-hydroxysteroid dehydrogenase 1: 3D-quantitative structure-activity relationship (3D-QSAR) and in silico docking analysis
Sailing Chen, Shaowei Wang, Jingyi Zheng, Lu Han, Huiqian Chen, Yunbing Tang, Nan Wang, Yang Zhu, Yiyan Wang, Ping Duan, Ren‐Shan Ge
Topics & Concepts
Quantitative structure–activity relationshipChemistryHydroxysteroid dehydrogenaseEnzymeEstroneDehydrogenaseDocking (animal)BisphenolStereochemistrySteroidBisphenol ABisphenol SIC50Endocrine disruptorMicrosomeBiochemistryHormoneIn vitroEndocrine systemOrganic chemistryNursingEpoxyMedicineEffects and risks of endocrine disrupting chemicalsEstrogen and related hormone effectsFree Radicals and Antioxidants