The evolution of mendelian randomization for investigating drug effects
Dipender Gill, Stephen Burgess
Abstract
Dipender Gill and Stephen Burgess discuss the accompanying study by James Yarmolinsky and colleagues investigating the associations between genetically-proxied inhibition of antihypertensive drug targets and risk of common cancer subtypes using Mendelian randomization.
Topics & Concepts
Mendelian randomizationMendelian inheritanceDrugMedicineBiologyGeneticsBioinformaticsPharmacologyGeneGenetic variantsGenotypeGenetic Associations and EpidemiologyPharmacogenetics and Drug MetabolismBioinformatics and Genomic Networks