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Four statistical frameworks for assessing an immune correlate of protection (surrogate endpoint) from a randomized, controlled, vaccine efficacy trial

Peter B. Gilbert, Youyi Fong, Nima S. Hejazi, Avi Kenny, Ying Huang, Marco Carone, David Benkeser, Dean Follmann

2024Vaccine20 citationsDOIOpen Access PDF

Topics & Concepts

Clinical endpointSurrogate endpointContext (archaeology)Vaccine efficacyClinical trialRandomized controlled trialStandardizationVaccine trialMedicineIntensive care medicineComputer scienceImmune systemImmunologyBiologyInternal medicineOperating systemPaleontologySARS-CoV-2 and COVID-19 ResearchVaccine Coverage and HesitancyStatistical Methods in Clinical Trials
Four statistical frameworks for assessing an immune correlate of protection (surrogate endpoint) from a randomized, controlled, vaccine efficacy trial | Litcius