Case of apparent mpox reinfection
John Golden, Lindsey Harryman, Megan Crofts, Peter Muir, Matthew Donati, Sophie Gillett, Charles Irish
Abstract
We present an apparent second episode of mpox (monkeypox) genital ulcerative disease in a non-immunosuppressed MSM (man who has sex with men) patient who had completely recovered from a primary mpox infection 4 months previously. The patient had also received a complete two-dose course of smallpox vaccination between the two presentations. This case highlights the importance of continuing to include mpox in the differential diagnoses for individuals presenting with genital or mucosal ulceration, regardless of assumed immunity derived from prior infection or vaccination.
Topics & Concepts
MedicineMonkeypoxVaccinationSex organDifferential diagnosisSmallpoxSmallpox vaccineImmunologyGenital wartsPediatricsDermatologySyphilisHuman immunodeficiency virus (HIV)PathologyVacciniaGeneticsRecombinant DNABiochemistryChemistryGeneBiologyPoxvirus research and outbreaksBacillus and Francisella bacterial researchHerpesvirus Infections and Treatments