Social behaviors and contextual memory of Vcp mutant mice are sensitive to nutrition and can be ameliorated by amino acid supplementation
Tzyy‐Nan Huang, Yu‐Tzu Shih, Si-Cih Lin, Yi‐Ping Hsueh
Abstract
-deficient mice, strengthening evidence for the role of protein synthesis in VCP function. Our study illustrates that genetic variation and nutrient factors cross-talk to influence neuronal and behavioral phenotypes.
Topics & Concepts
MutantAmino acidChemistryPsychologyBiochemistryGeneChild Nutrition and Feeding IssuesNeuroendocrine regulation and behaviorChild Nutrition and Water Access