Anti-neuropathic pain activity of Ajugarin-I via activation of Nrf2 signaling and inhibition of TRPV1/TRPM8 nociceptors in STZ-induced diabetic neuropathy
Adnan Khan, Feng Wang, Bushra Shal, Ashraf Ullah Khan, Syeda Saniya Zahra, Ihsan Ul Haq, Salman Khan, Kannan R. R. Rengasamy
Topics & Concepts
TRPV1Transient receptor potential channelNeuropathic painMedicineTRPM8StreptozotocinNociceptionEndocrinologyCapsaicinNociceptorInternal medicineOxidative stressDiabetic neuropathyHeme oxygenasePharmacologyReceptorDiabetes mellitusChemistryHemeEnzymeBiochemistryPain Mechanisms and TreatmentsIon Channels and ReceptorsPharmacological Effects of Natural Compounds