RNA base editing therapy cures hearing loss induced by OTOF gene mutation
Yuanyuan Xue, Yong Tao, Xing Wang, Xueling Wang, Yilai Shu, Yuanhua Liu, Wen Kang, Sifan Chen, Zhenzhe Cheng, Boou Yan, Yanwei Xie, Lanting Bi, Haitao Jia, Jinhui Li, Qingquan Xiao, Liying Chen, Xuan Yao, Linyu Shi, Hui Yang, Hao Wu
Topics & Concepts
Auditory neuropathyHearing lossBiologyMutationPopulationGeneticsStop codonGeneAudiologyMedicineEnvironmental healthRNA regulation and diseaseCRISPR and Genetic EngineeringRNA and protein synthesis mechanisms