Efficient detection of<scp>l</scp>-aspartic acid and<scp>l</scp>-glutamic acid by self-assembled fluorescent microparticles with AIE and FRET activities
Wenjuan Qu, Tingting Liu, Yongping Chai, Dongyan Ji, Yu‐Xin Che, Jianpeng Hu, Hong Yao, Qi Lin, Tai‐Bao Wei, Bingbing Shi
Abstract
Amino acids play an important role in the formation of proteins, enzymes, hormones and peptides in animals. Moreover, aspartic acid and glutamic acid have a critical impact on the central nervous system as excitatory neurotransmitters. Here, we report the highly selective detection of L-glutamic acid (L-Glu) and L-aspartic acid (L-Asp) using fluorescent microparticles constructed by the combination of aggregation-induced emission and self-assembly-induced Förster resonance energy transfer.
Topics & Concepts
Förster resonance energy transferFluorescenceChemistryGlutamic acidBiochemistryBiophysicsAmino acidBiologyPhysicsQuantum mechanicsLuminescence and Fluorescent MaterialsMolecular Sensors and Ion DetectionAdvanced biosensing and bioanalysis techniques