Modulatory Role of Quercetin in Mitochondrial Dysfunction in Titanium Dioxide Nanoparticle-Induced Hepatotoxicity
Mohd Waseem, Pooja Kaushik, Shamita Dutta, Rohan Chakraborty, Md. Imtaiyaz Hassan, Suhel Parvez
Abstract
Based on the findings, we conclude that QR, which mitigates oxidative stress caused by mitochondrial dysfunction, holds promising capability to potentially diminish TNP-induced adverse effects in the liver.
Topics & Concepts
Oxidative stressMitochondrionAntioxidantChemistryLipid peroxidationOxidative phosphorylationMitochondrial toxicityToxicityEnzymeBiochemistryPharmacologyRespiratory chainReactive oxygen speciesBiologyOrganic chemistryCurcumin's Biomedical ApplicationsMedicinal Plants and NeuroprotectionPhytochemicals and Antioxidant Activities