Three new coordination geometries of homoleptic Zn complexes of curcuminoids and their high antiproliferative potential
William Meza-Morales, Yair Alvarez-Ricardo, Marco A. Obregón‐Mendoza, Antonino Arenaza‐Corona, María Teresa Ramírez‐Apán, Rubén A. Toscano, Juan Carlos Poveda-Jaramillo, Raúl G. Enríquez
Abstract
We add herein three new geometries of homoleptic type complexes i.e. octahedral, trigonal-pyramidal, and trigonal-bipyramidal. Moreover, the IC 50 values for the DiMeOC-Zn complex were 8 or 22 times higher than cisplatin in the U251 and HCT15 cell lines.
Topics & Concepts
HomolepticTrigonal bipyramidal molecular geometryOctahedronChemistryCrystallographyTrigonal crystal systemTrigonal prismatic molecular geometryStereochemistryMetalCrystal structureOrganic chemistryCurcumin's Biomedical ApplicationsNatural product bioactivities and synthesisMetal complexes synthesis and properties