Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms
Tongwu Zhang, Jiyeon Choi, Ramile Dilshat, Berglind O. Einarsdottir, Michael A. Kovacs, Mai Xu, Michael Malasky, Salma Chowdhury, Kristine Jones, D. Timothy Bishop, Alisa M. Goldstein, Mark M. Iles, Maria Teresa Landi, Matthew H. Law, Jianxin Shi, Eirı́kur Steingrı́msson, Kevin M. Brown
Topics & Concepts
Expression quantitative trait lociGenome-wide association studyBiologyQuantitative trait locusGeneticsCandidate geneDNA methylationGeneSingle-nucleotide polymorphismGene expressionGenotypeGenetic Associations and EpidemiologyEpigenetics and DNA MethylationGenetic Mapping and Diversity in Plants and Animals