Visible‐Light‐Enabled Photosensitizer‐ and Additive‐Free Decarboxylative Coupling Cyclization of Enaminone with <i>N</i>‐Arylglycine for 3‐Aminoalkyl Chromones
Zhiqiang Zhu, Jia‐Yu Hu, Zongbo Xie, Juan Tang, Zhanggao Le
Abstract
Abstract An photosensitizer‐ and additive‐free, visible‐light‐induced decarboxylative aminoalkylation/C−O coupling cyclization of enaminones with N ‐arylglycine for the synthesis of 3‐aminoalkyl chromones has been achieved. This synthetic method features good functional‐group tolerance, mild reaction conditions and no request of photocatalyst or additive, thus making this protocol more practical and sustainable. magnified image
Topics & Concepts
ChemistryPhotosensitizerPhotochemistryPhotocatalysisVisible spectrumFunctional groupCoupling (piping)Combinatorial chemistryDecarboxylationOrganic chemistryCatalysisOptoelectronicsPolymerMechanical engineeringPhysicsEngineeringSynthesis of Organic CompoundsRadical Photochemical ReactionsCatalytic C–H Functionalization Methods