Litcius/Paper detail

Real-time effects of Cd(<scp>ii</scp>) on the cellular membrane permeability

Biao Zhang, Na Pan, Xiaoyin Fan, Liping Lü, Xiayan Wang

2021The Analyst12 citationsDOI

Abstract

for a short time. However, the cell membranes were irreversibly damaged when the cytoskeleton structures were destroyed, and the cell activities decreased at high concentrations over long periods. Interestingly, through the comparison with an x-scan study, it was found that DPV technology shows a higher performance in the detection of changes in the membrane permeability. Using a combination of cytoskeleton fluorescence imaging and cell-viability tests, the effect of the cadmium metal on the cell membrane permeability can be explored deeper and more comprehensively. This study provides a new idea for exploring the changes in the cell membrane permeability and may be helpful for rapid evaluation of cytotoxicity.

Topics & Concepts

Permeability (electromagnetism)ChemistryMembraneIn situMembrane permeabilityBiophysicsChromatographyBiochemistryBiologyOrganic chemistryElectrochemical Analysis and ApplicationsAdvanced biosensing and bioanalysis techniquesTrace Elements in Health