Characteristics of mesenteric adipose tissue attached to different intestinal segments and their roles in immune regulation
Haowei Zhang, Yujin Ding, Qin Zeng, Dandan Wang, Ganglei Liu, Zain S Hussain, Boen Xiao, Wei Liu, Tuo Deng
Abstract
Our results change the paradigm of how we regard MAT as a contiguous and homogeneous tissue to an intensely heterogeneous tissue. Appreciation of the differences between regional MATs will guide future research to investigate the specialized roles of different MATs in intestinal health and disease.
Topics & Concepts
Adipose tissueHomogeneousImmune systemBiologyDiseasePathologyMedicineImmunologyEndocrinologyPhysicsThermodynamicsImmune cells in cancerIL-33, ST2, and ILC PathwaysCardiovascular Disease and Adiposity