Litcius/Paper detail

Adipose-derived mesenchymal stem cell seeded Atelocollagen scaffolds for cardiac tissue engineering

Qiong Li, Miaomiao Li, Meng Li, Zhengyan Zhang, Han Ma, Liang Zhao, Min Zhang, Guodong Wang

2020Journal of Materials Science Materials in Medicine17 citationsDOIOpen Access PDF

Abstract

ADMSCs were isolated from subcutaneous adipose tissue, characterized and cultured in vitro. GFP-labeled ADMSCs can grow and proliferate well on the Atelocollagen scaffolds, and induced by 5-aza the cells can differentiate into cardio-like cells. 3D cultured ADMSCs on Atelocollagen scaffolds were transplanted into mice ischemia myocardium, and have good biocompatibility with host cardio tissue.

Topics & Concepts

Mesenchymal stem cellAdipose tissueTissue engineeringCell biologyBiocompatibilityIn vitroStem cellScaffoldTransplantationBiomedical engineeringChemistryMedicineBiologyBiochemistryInternal medicineOrganic chemistryTissue Engineering and Regenerative MedicineElectrospun Nanofibers in Biomedical ApplicationsMuscle Physiology and Disorders