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1,25-dihydroxyvitamin D3 induces stable and reproducible therapeutic tolerogenic dendritic cells with specific epigenetic modifications

Kayleigh M. van Megen, Zhuo Chen, Antoinette M. Joosten, Sandra Laban, Jaap Jan Zwaginga, Rama Natarajan, Tatjana Nikolić, Bart O. Roep

2021Cytotherapy21 citationsDOIOpen Access PDF

Topics & Concepts

EpigeneticsDNA methylationImmune systemTranscriptomeEpigenomeImmunologyPhenotypeAntigenBiologyGeneGene expressionGeneticsImmune Cell Function and InteractionDiabetes and associated disordersT-cell and B-cell Immunology
1,25-dihydroxyvitamin D3 induces stable and reproducible therapeutic tolerogenic dendritic cells with specific epigenetic modifications | Litcius