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CagA and VacA inhibit gastric mucosal epithelial cell autophagy and promote the progression of gastric precancerous lesions.

Jiaxiang Zhang, Wenba Wang, Shuguang Yan, Jingtao Li, Hailiang Wei, Weihan Zhao

2022PubMed12 citationsDOIOpen Access PDF

Abstract

-related severe gastric diseases, and a variety of drugs or components that can precisely and effectively regulate the factors for the treatment of gastric precancerous lesions are emerged, which opens a new strategy for the treatment of gastric precancerous lesions in the future.

Topics & Concepts

CagAAutophagyHelicobacter pyloriApoptosisDNA damageGastric mucosaBiologyCancerInflammationCancer researchMicrobiologyImmunologyStomachGeneDNAVirulenceGeneticsBiochemistryHelicobacter pylori-related gastroenterology studiesGalectins and Cancer BiologyRNA modifications and cancer
CagA and VacA inhibit gastric mucosal epithelial cell autophagy and promote the progression of gastric precancerous lesions. | Litcius