Light-Induced Difunctionalization of Alkenes with Polyhaloalkanes and Quinoxalin-2(1<i>H</i>)-ones

Abstract

Herein, we report a metal-free light-induced three-component reaction for the synthesis of polychloroalkyl-substituted quinoxalin-2(1 H )-ones using commercially available alkenes, polyhalo alkanes, and quinoxalin-2(1 H )-ones. Preliminary mechanistic studies suggested the generation of radical intermediates via an EDA-complex, single electron transfer, or halogen atom transfer pathway. Under mild reaction conditions, various alkenes and quinoxalin-2(1 H )-ones containing different functional groups are compatible, providing the corresponding polychloroalkyl-substituted quinoxalin-2(1 H )-ones in moderate to good yields.

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