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A Transcriptional Regulatory Map of Iron Homeostasis Reveals a New Control Circuit for Capsule Formation in <i>Cryptococcus neoformans</i>

Eunsoo Do, Yong‐Joon Cho, Donghyeun Kim, James W. Kronstad, Won Hee Jung

2020Genetics31 citationsDOIOpen Access PDF

Abstract

Abstract To overcome host iron restriction, the human fungal pathogen Cryptococcus neoformans uses several iron uptake mechanisms to cause disease. In this study....

Topics & Concepts

Cryptococcus neoformansBiologyFungal pathogenIron homeostasisCryptococcosisCryptococcusPathogenMicrobiologyGeneticsGeneHomeostasisHost (biology)Cell biologyFungal Infections and StudiesPhytoplasmas and Hemiptera pathogensParasitic Infections and Diagnostics