Expression of DNA Methyltransferase 1 Is a Hallmark of Melanoma, Correlating with Proliferation and Response to B-Raf and Mitogen-Activated Protein Kinase Inhibition in Melanocytic Tumors
Maximilian Gassenmaier, Maximilian Rentschler, Birgit Fehrenbacher, Thomas Eigentler, Kristian Ikenberg, Corinna Kosnopfel, Tobias Sinnberg, Heike Niessner, Hans Bösmüller, Nikolaus B. Wagner, Martin Schaller, Claus Garbe, Martin Röcken
Topics & Concepts
DNA methyltransferaseDNMT1Cancer researchEpigeneticsMelanomaBiologyDNA methylationMethyltransferaseMolecular biologyCell growthMethylationGene expressionDNAGeneticsGeneEpigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics