Landscape of <i>FGF</i>/<i>FGFR</i> Alterations in 12,372 Chinese Cancer Patients
Wei Zuo, Yan He, Wei Li, Hao Wu, Zhengyi Zhao, Yuzi Zhang, Shiqing Chen, Yongmei Yin
Abstract
The aberrant of fibroblast growth factors and their receptors (FGF/FGFR) is an emerging target in the treatment of solid tumors. This study aimed to explore the landscape of FGF/FGFR alterations in a large cohort of cancer patients.
Topics & Concepts
Fibroblast growth factor receptorFibroblast growth factorCancerMedicineCancer researchGenome instabilityInternal medicineOncologyReceptorBiologyGeneticsDNADNA damageFibroblast Growth Factor ResearchEpigenetics and DNA MethylationMedical Imaging and Pathology Studies