Intracellular metal ion-based chemistry for programmed cell death
Y You, Zhongying Guo, Tyler Wolter, Quanyin Hu
Abstract
) are briefly discussed. Further, this review elaborates on the underlying chemical mechanisms and summarizes these metal ions triggering PCD in cancer therapy. This review bridges chemistry, immunology, and biology to foster the rational regulation of metal ions to induce PCD for cancer therapy.
Topics & Concepts
IntracellularChemistryMetalBiophysicsMetal ions in aqueous solutionIonCell membraneCellProgrammed cell deathCalcium in biologyCell biologyBiochemistryBiologyApoptosisOrganic chemistryTrace Elements in HealthMetal complexes synthesis and propertiesMolecular Sensors and Ion Detection