Inert cationic iridium(<scp>iii</scp>) complexes with phenanthroline-based ligands: application in antimicrobial inactivation of multidrug-resistant bacterial strains
Natalia Busto, Gloria Vigueras, N. Cutillas, Begoña Garcı́a, José Ruiz
Abstract
remained intact on treatment with these compounds and that DNA was not their main target. It is important to note that the complexes were able to induce ROS generation, this being the feature key to their antimicrobial activity.
Topics & Concepts
ChemistryAntimicrobialEnterococcus faeciumStaphylococcus aureusMicrobiologyMultiple drug resistancePseudomonas aeruginosaBacteriaAntibioticsBiochemistryBiologyOrganic chemistryGeneticsAntibiotic Resistance in BacteriaCancer therapeutics and mechanismsSynthesis and Biological Evaluation