Microdissection of cancer-associated fibroblast infiltration subtypes unveils the secreted SERPINE2 contributing to immunosuppressive microenvironment and immuotherapeutic resistance in gastric cancer: A large-scale study integrating bulk and single-cell transcriptome profiling
Dong Zhang, Rui Sun, C. Di, Lin Li, Faming Zhao, Yu Han, Wenjie Zhang
Topics & Concepts
Tumor microenvironmentStromal cellImmunotherapyCancer-Associated FibroblastsCancer researchImmune systemBiologyCancerCancer immunotherapyTranscriptomeImmunologyGeneGene expressionGeneticsBiochemistryCancer Immunotherapy and BiomarkersImmune cells in cancerFerroptosis and cancer prognosis