Decreased Proteasomal Function Induces Neuronal Loss and Memory Impairment
Utano Tomaru, Tomoki� Ito, Yu Ohmura, Kei Higashikawa, Syota Miyajima, Ruka Tomatsu, Tsunehito Higashi, Akihiro Ishizu, Yuji Kuge, Mitsuhiro Yoshioka, Masanori Kasahara
Topics & Concepts
ProteostasisProteasomeUnfolded protein responseEndoplasmic reticulumCell biologyProgrammed cell deathApoptosisMemory impairmentBiologyNeuroscienceBiochemistryCognitionEndoplasmic Reticulum Stress and DiseaseAlzheimer's disease research and treatmentsUbiquitin and proteasome pathways