SNS ligand-assisted catalyst activation in Zn-catalysed carbonyl hydroboration
Saeed Ataie, Seth Hogeterp, Jeffrey S. Ovens, R. Tom Baker
Abstract
Ligands that include Lewis acid/base functionality have extensive applications in bifunctional catalysis using first row metals. In this work, zinc bis(amido), bis(thiolate) and amido-thiolate SNS complexes were prepared and compared as precatalysts for carbonyl hydroboration using pinacolborane. Mechanistic studies revealed two different ligand-assisted precatalyst activation pathways, both leading to an active and robust zinc alkoxide catalyst. This work furthers our understanding of metal-ligand cooperation in first-row metal catalysis.
Topics & Concepts
HydroborationChemistryCatalysisLigand (biochemistry)BifunctionalZincAlkoxideLewis acids and basesMetalCombinatorial chemistryPolymer chemistryOrganic chemistryReceptorBiochemistryChemical Synthesis and ReactionsOrganoboron and organosilicon chemistryAsymmetric Hydrogenation and Catalysis