Overexpression of SIRT6 regulates NRF2/HO-1 and NF-κB signaling pathways to alleviate UVA-induced photoaging in skin fibroblasts
Tao Wang, Yonghong Qin, Jianxiong Qiao, Yang Liu, Lerong Wang, Xuanfen Zhang
Topics & Concepts
PhotoagingSIRT6Skin AgingGene knockdownSignal transductionCell biologyDownregulation and upregulationNF-κBOxidative stressChemistryHuman skinSenescenceCancer researchDermal fibroblastMelaninFibroblastBiologySirtuinApoptosisMedicineIn vitroAcetylationGeneBiochemistryDermatologyGeneticsSkin Protection and AgingSirtuins and Resveratrol in MedicineGenomics, phytochemicals, and oxidative stress