Copper‐Catalyzed Four‐Component Cascade Reaction for the Construction of Triazoles Bearing β‐Hydroxy Chalcogenides
Xiangxiang Wang, Bo‐Xun Sun, Zhiwei Zhao, Xin Chen, Wen‐Jin Xia, Yuehai Shen, Ya‐Min Li
Abstract
Abstract A copper‐catalyzed four‐component cascade reaction for the preparation of triazoles bearing β‐hydroxy chalcogenides from terminal alkynes, azides, epoxides, and Se/K 2 S is reported. The present reaction proceeds under mild conditions, and exhibits a good functional group compatibility. A possible mechanism is proposed. magnified image
Topics & Concepts
ChemistryCascadeCatalysisCompatibility (geochemistry)CopperBearing (navigation)Component (thermodynamics)Combinatorial chemistryCascade reactionReaction conditionsPolymer chemistryOrganic chemistryChemical engineeringGeographyThermodynamicsEngineeringCartographyPhysicsChromatographyClick Chemistry and ApplicationsSulfur-Based Synthesis TechniquesSynthesis and Catalytic Reactions