Litcius/Paper detail

Inhibition of GPR17 with cangrelor improves cognitive impairment and synaptic deficits induced by Aβ1–42 through Nrf2/HO-1 and NF-κB signaling pathway in mice

Shiyu Jin, Xin Wang, Xiaotong Xiang, Yumei Wu, Jie Hu, Yueyue Li, Yue Lin Dong, YueQiang Tan, Xian Wu

2021International Immunopharmacology34 citationsDOI

Topics & Concepts

CangrelorNeurotoxicityNeuroinflammationMicrogliaPharmacologyOxidative stressSuperoxide dismutaseHippocampusMedicineChemistryInflammationInternal medicineToxicityConventional PCIPrasugrelMyocardial infarctionAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders