The citrus flavonoid, nobiletin inhibits neuronal inflammation by preventing the activation of NF-κB
Taisuke Murata, Sho Ishiwa, Xin Lin, Yosuke Nakazawa, Kenji Tago, Megumi Funakoshi‐Tago
Topics & Concepts
NobiletinMicrogliaNeuroinflammationPharmacologyChemistryNitric oxide synthasep38 mitogen-activated protein kinasesLipopolysaccharideNitric oxideNF-κBProstaglandin E2InflammationTumor necrosis factor alphaMAPK/ERK pathwayBiochemistryBiologyFlavonoidPhosphorylationSignal transductionEndocrinologyImmunologyAntioxidantOrganic chemistryBioactive Compounds in PlantsNeurological Disease Mechanisms and TreatmentsBioactive natural compounds