Lactobacillus reuteri attenuates methotrexate-induced liver injury via modulation of oxidative stress and inflammation through HO-1/GPX4 and NF-κB/NLRP3 pathways
Wenjun Li, Yike Li, Huan Ren, Zhen Guo, Chen‐Lin Xiao, Jian‐Quan Luo
Topics & Concepts
Lactobacillus reuteriGut floraLiver injuryOxidative stressInflammationPharmacologyBiologyImmunologyGlutathioneDysbiosisLactobacillusMicrobiologyMedicineAntibioticsProinflammatory cytokineInternal medicineFatty liverChemotherapy-induced organ toxicity mitigationDrug-Induced Hepatotoxicity and ProtectionGenomics, phytochemicals, and oxidative stress