6-methoxyflavone suppresses neuroinflammation in lipopolysaccharide- stimulated microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF-κB dependent pathways and the activation of HO-1/NQO-1 signaling
Wu-Fu Chen, Yao‐Hsiang Shih, Hsuan-Chih Liu, Cheng‐I Cheng, Chi‐I Chang, Chung‐Yi Chen, In-Pin Lin, Mei-Ying Lin, Chien‐Hsing Lee
Topics & Concepts
NeuroinflammationMicrogliap38 mitogen-activated protein kinasesMAPK/ERK pathwayTLR4LipopolysaccharideChemistryNeuroprotectionNF-κBCell biologyPharmacologySignal transductionInflammationBiologyImmunologyNeuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and TreatmentsBioactive natural compounds