MYOCD and SMAD3/SMAD4 form a positive feedback loop and drive TGF-β-induced epithelial–mesenchymal transition in non-small cell lung cancer
Xin Tong, Shengjie Wang, Zhe Lei, Chang Li, Cuijuan Zhang, Zhiyue Su, Xia Liu, Jun Zhao, Hongtao Zhang
Topics & Concepts
Epithelial–mesenchymal transitionGene knockdownCancer researchBiologyGene silencingDownregulation and upregulationTransforming growth factorMetastasisSmall hairpin RNAInternal medicineCancerEndocrinologyCell cultureMedicineGeneBiochemistryGeneticsTGF-β signaling in diseasesGenetic factors in colorectal cancerCancer Cells and Metastasis