Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress
Xuejiao Xiang, Jing Chen, Tao Jiang, Chengqi Yan, Yu Kang, Maojie Zhang, Kaituo Xiang, Jiahe Guo, Guoyong Jiang, Cheng Wang, XiangXu, Xiaofan Yang, Zhenbing Chen
Topics & Concepts
KEAP1Oxidative stressUmbilical veinWound healingGene knockdownStreptozotocinMicrovesiclesMethylglyoxalMedicineDownregulation and upregulationPharmacologyApoptosisHuman umbilical vein endothelial cellDiabetes mellitusCancer researchChemistryImmunologyInternal medicineBiochemistryEndocrinologymicroRNAIn vitroTranscription factorEnzymeGeneWound Healing and TreatmentsExtracellular vesicles in diseaseBurn Injury Management and Outcomes