Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Qin Cao, David R. Boyer, M.R. Sawaya, Romany Abskharon, Lorena Saelices, Binh A. Nguyen, Jiahui Lu, Kevin A. Murray, Fouad Kandeel, David Eisenberg
Topics & Concepts
FibrilCollagen fibrilBiophysicsChemistryCrystallographyAmyloid fibrilBiologyAmyloid βMedicinePathologyDiseaseConnective tissue disorders researchNuclear Structure and FunctionEnzyme Structure and Function