Hypoxia-induced USP22-BMI1 axis promotes the stemness and malignancy of glioma stem cells via regulation of HIF-1α
Guanzhong Qiu, Qiang Liu, Xiaogang Wang, Guang-Zhen Xu, Tong Zhao, Meiqing Lou
Topics & Concepts
BMI1Stem cellBiologyFlow cytometryCancer researchApoptosisCell growthGene silencingWestern blotHaematopoiesisGliomaHypoxia (environmental)Molecular biologyChemistryCell biologyBiochemistryGeneOrganic chemistryOxygenCancer, Hypoxia, and MetabolismUbiquitin and proteasome pathwaysMicrotubule and mitosis dynamics