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The Bacterial MtrAB Two-Component System Regulates the Cell Wall Homeostasis Responding to Environmental Alkaline Stress

Xiaoyu Qin, Kaiduan Zhang, Yuzhao Fan, Hui Fang, Yong Nie, Xiao‐Lei Wu

2022Microbiology Spectrum78 citationsDOIOpen Access PDF

Abstract

sp. DQ12-45-1b plays a critical role in alkaline resistance by modulating the cell wall homeostasis through the MtrAB-MraZ pathway. Thus, our work provides a novel regulatory pathway used by bacteria for adaptation and survival under extreme alkaline stresses.

Topics & Concepts

Environmental stressComponent (thermodynamics)HomeostasisBacteriaBiologyMicroorganismRange (aeronautics)EcologyCell biologyGeneticsEngineeringAerospace engineeringThermodynamicsPhysicsMicrobial Community Ecology and PhysiologyBacterial Genetics and BiotechnologyBacterial biofilms and quorum sensing
The Bacterial MtrAB Two-Component System Regulates the Cell Wall Homeostasis Responding to Environmental Alkaline Stress | Litcius