Long-term stable reduction of low-density lipoprotein in nonhuman primates following in vivo genome editing of PCSK9
Lili Wang, Camilo Breton, Claude C. Warzecha, Peter Bell, Hanying Yan, Zhenning He, John White, Yanqing Zhu, Mingyao Li, Elizabeth L. Buza, Derek Jantz, James M. Wilson
Topics & Concepts
PCSK9Genome editingIn vivoBiologyTerm (time)Reduction (mathematics)LDL receptorGenomeGeneticsLipoproteinGeneCholesterolEndocrinologyQuantum mechanicsPhysicsGeometryMathematicsViral Infections and Immunology ResearchCRISPR and Genetic EngineeringRNA regulation and disease