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Electrochemical stereoselective synthesis of polysubstituted 1,4-dicarbonyl <i>Z</i>-alkenes <i>via</i> three-component coupling of sulfoxonium ylides and alkynes with water

Haoran Li, Yi-An Ran, Yu-Yi Zhu, Weisi Guo, Shao‐Fei Ni, Li‐Rong Wen, Ming Li, Lin‐Bao Zhang

2024Chemical Science14 citationsDOIOpen Access PDF

Abstract

-stereoselectivity, which is rare in previous cases. The proposed reaction mechanism was convincingly established by carrying out a series of control experiments, cyclic voltammetry experiments, and density functional theory (DFT) studies.

Topics & Concepts

StereoselectivityComponent (thermodynamics)ElectrochemistryCoupling (piping)ChemistryCombinatorial chemistryOrganic chemistryMedicinal chemistryMaterials scienceElectrodeCatalysisPhysicsPhysical chemistryMetallurgyThermodynamicsCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques