An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2
Katherine C. Barnett, Yuying Xie, Takanori Asakura, Dingka Song, Kaixin Liang, Sharon Taft-Benz, Haitao Guo, Shuangshuang Yang, Kenichi Okuda, Rodney C. Gilmore, Jennifer F. Loome, Thomas H. Oguin, Gregory D. Sempowski, Scott H. Randell, Mark T. Heise, Yu L. Lei, Richard C. Boucher, Jenny P.‐Y. Ting
Topics & Concepts
InflammasomeBiologyAIM2Immune systemSecretionImmunologyCytokinePyroptosisInnate immune systemInflammationTLR2Caspase 1Respiratory epitheliumCell biologyEpitheliumGeneticsBiochemistryInflammasome and immune disordersCOVID-19 Clinical Research Studiesinterferon and immune responses