Astrocytes contribute to pain gating in the spinal cord
Qian Xu, Neil C. Ford, Shaoqiu He, Qian Huang, Michael Anderson, Zhiyong Chen, Fei Yang, LaTasha K. Crawford, Michael J. Caterina, Yun Guan, Xinzhong Dong
Abstract
neurons and pain inhibition by Aβ-fiber stimulation. Collectively, our study introduces astrocytes as an important component of pain gating by activation of Aβ-fibers, which thus exert nonneuronal control of pain.
Topics & Concepts
Spinal cordGatingNeuroscienceMedicineAstrocyteBiologyCentral nervous systemPain Mechanisms and TreatmentsNerve injury and regenerationVagus Nerve Stimulation Research